Studies of Cytotoxic Potential of Aqueous Fruit Extract of Cucumis melo.Linn in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay

The objective of the study was to evaluate the cytotoxic effects of aqueous extract of Cucumis melo fruit on human prostate cancer cell line (PC-3) using MTT and neutral red assays. The crude aqueous extract of C. melo was prepared by cold maceration method, filtered, concentrated and tested on PC-3 cell line. Dose-dependent cytotoxic activities were exhibited on human prostate carcinoma PC-3 cell line. As the dose of the extract increased, the number of viable cells decreased. This confirms the cytotoxic potential of the fruit of C. melo.